Priming the sample manager

Priming the sample manager is part of the system startup workflow on the touchscreen.

Priming fills the wash system with wash solvent or the injection pathway with mobile phase. You prime the system to accomplish these tasks:

• Preparing a new sample manager for operation
• Preparing a sample manager for operation after it has been idle for more than 24 hours
• Changing the wash solvent
• Removing bubbles from the lines

Ensure that the wash solvent is correctly composed, that it is of LC-MS grade, and that it is miscible with other solvents used in the system. Use filters in all solvent reservoirs, and ensure that the volumes of solvents suffice for priming.

To prime the sample metering pump and wash solvent:

1. On the touchscreen, tap Setup > Solvents > Prime Sample Metering Pump and follow the on-screen prompts..
2. Follow the remainder of the on-screen prompts to finish the system startup process.